<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G/A</submissionType>
    <previousAccessionNumber>0001477932-25-001068</previousAccessionNumber>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001744816</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <amendmentNo>2</amendmentNo>
      <securitiesClassTitle>Common Stock, $0.01 par value</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>12/31/2024</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001921865</issuerCik>
        <issuerName>ASP Isotopes Inc.</issuerName>
        <issuerCusip>00218A105</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>601 PENNSYLVANIA AVENUE NW</com:street1>
          <com:street2>SOUTH BUILDING, SUITE 900</com:street2>
          <com:city>WASHINGTON</com:city>
          <com:stateOrCountry>DC</com:stateOrCountry>
          <com:zipCode>20004</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(d)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Mann Paul Elliot</reportingPersonName>
      <citizenshipOrOrganization>X0</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>7712982.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>7712982.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>7712982.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>10.8</classPercent>
      <typeOfReportingPerson>IN</typeOfReportingPerson>
      <comments>Items 5, 7 and 9 - 6,824,093 shares of Common Stock held directly by Paul Mann and (2) 1,104,889 shares of Common Stock issuable upon the exercise of warrants exercisable within 60 days of December 31, 2024.
Item 11 - This percentage calculation is based on 71,390,107 outstanding shares as of November 13, 2024, as set forth in the Issuer's Quarterly Report on Form 10-Q as filed with the SEC on November 19, 2024.</comments>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>ASP Isotopes Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>601 PENNSYLVANIA AVENUE NW, SOUTH BUILDING, SUITE 900, WASHINGTON, DISTRICT OF COLUMBIA, 20004.</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>Paul E. Mann</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>601 Pennsylvania Avenue NW, South Building, Suite 900, Washington DC 20004</principalBusinessOfficeOrResidenceAddress>
        <citizenship>United Kingdom</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>N</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>7,712,982 shares</amountBeneficiallyOwned>
        <classPercent>10.8</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>7,712,982 shares</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>0</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>7,712,982 shares</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>0</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>Y</notApplicableFlag>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>Mann Paul Elliot</reportingPersonName>
      <signatureDetails>
        <signature>/s/ Paul E. Mann</signature>
        <title>Paul E. Mann</title>
        <date>02/14/2025</date>
      </signatureDetails>
    </signatureInformation>
  </formData>
</edgarSubmission>