Name of Subsidiary

Jurisdiction of Incorporation or Organization

Orchard Therapeutics (Europe) Limited

England and Wales

Orchard Therapeutics North America

California (United States)

Orchard Therapeutics (Netherlands) B.V.

Netherlands

Orchard Therapeutics (France) SAS

France

Orchard Therapeutics (Italy) S.r.l

Italy

Orchard Therapeutics (Germany) GmbH

Germany

Orchard Therapeutics (Switzerland) GmbH

Switzerland

Orchard Therapeutics (Sweden) AB

Sweden