Exhibit 23.1
Consent of Independent Registered Public Accounting Firm
We consent to the incorporation by reference in the following Registration Statements:
(1)
Registration Statement (Form S-8 No. 333-234357) pertaining to the 2019 Equity Incentive Plan, 2019 Incentive Award Plan, and 2019 Employee Stock Purchase Plan of Phathom Pharmaceuticals, Inc.,
(2)
Registration Statement (Form S-8 No. 333-263420) pertaining to the 2019 Incentive Award Plan and 2019 Employee Stock Purchase Plan of Phathom Pharmaceuticals, Inc.,
(3)
Registration Statement (Form S-3 No. 333-275431) of Phathom Pharmaceuticals, Inc.,
(4)
Registration Statement (Form S-8 No. 333-285617) pertaining to the 2019 Incentive Award Plan and the 2019 Employee Stock Purchase Plan of Phathom Pharmaceuticals, Inc., and
(5)
Registration Statement (Form S-3ASR No. 333-292596) of Phathom Pharmaceuticals, Inc.
of our report dated February 26, 2026, with respect to the financial statements of Phathom Pharmaceuticals, Inc. included in this Annual Report (Form 10-K) of Phathom Pharmaceuticals, Inc. for the year ended December 31, 2025.
/s/ Ernst & Young
Iselin, New Jersey
February 26, 2026