Annex G
AMENDED AND RESTATED SUBSCRIPTION AGREEMENT
This Amended and Restated Subscription Agreement (this “Agreement”) is made and entered into as of September 2, 2026 (the “Effective Date”) by and among Remix Therapeutics, Inc., a Delaware corporation
(the “Company”), and each of the purchasers listed on the Schedule of Purchasers attached hereto, severally and not jointly (each a “Purchaser” and together the “Purchasers”). Certain terms used and not otherwise defined in the text of this Agreement are defined in Section 8
hereof.
RECITALS
WHEREAS, the Company is party to that certain Agreement and Plan of Merger by
and among the Company, Peregrine Merger Sub, Inc. (“Merger Sub”), and Passage Bio, Inc. (“Passage”), dated as of June 24, 2026
(the “Merger Agreement”), pursuant to which Merger Sub will merge with and into the Company, with the Company surviving as a wholly-owned subsidiary of Passage (the “Merger”);
WHEREAS, the Company and the Purchasers are party to that certain Subscription
Agreement, dated as of June 24, 2026 (the “Original Agreement”);
WHEREAS, the Company and each Purchaser, in accordance with Section 9.01
of the Original Agreement, desire to amend and restate the Original Agreement as hereinafter set forth in order to provide for the purchase of pre-funded warrants to purchase shares of Common Stock (as defined below) in lieu of shares of Common
Stock;
WHEREAS, the Company desires to sell to the Purchasers, and the Purchasers,
severally and not jointly, desire to purchase from the Company, an aggregate amount equal to $69,999,999.28 (the “Total Subscription Amount”) of (A) shares of the Company’s Common Stock,
par value $0.0001 per share (the “Common Stock”) and/or (B) pre-funded warrants to purchase shares of Common Stock, in substantially the form attached hereto as Exhibit A (the “Pre-Funded Warrants”);
WHEREAS, the Company and each Purchaser is executing and delivering this
Agreement in reliance upon the exemption from securities registration afforded by Section 4(a)(2) of the 1933 Act and/or in reliance upon any of the safe harbors set forth in Regulation D thereunder; and
WHEREAS, at the Initial Effective Time (as defined in the Merger Agreement) by
virtue of the Merger, the shares of Common Stock shall be automatically converted into the right to receive a number of shares of common stock par value $0.0001 per share, of Passage (the “Passage
Common Stock”), and the Pre-Funded Warrants shall cease to represent a right to acquire shares of Common Stock and shall be converted into a pre-funded warrant to purchase shares of Passage Common Stock, in accordance with Section 2.4(d)
and Section 2.4(i), respectively, of the Merger Agreement.
NOW, THEREFORE, in consideration of the foregoing and the mutual
representations, warranties and covenants herein contained, the parties hereto hereby agree as follows:
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SECTION 1.
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Authorization of Securities.
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1.01
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The Company has authorized the sale and issuance of shares of Common Stock and the Pre-Funded Warrants on the terms and subject
to the conditions set forth in this Agreement. The shares of Common Stock sold hereunder at the Closing (as defined below) shall be referred to as the “Shares”, the shares of
Common Stock issuable upon exercise of or otherwise pursuant to the Pre-Funded Warrants shall be referred to as the “Warrant Shares” and the Shares and the Pre-Funded Warrants
(including, as applicable, the Warrant Shares issuable in exchange therefor) shall be collectively referred to as the “Securities”.
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SECTION 2.
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Sale and Purchase of the Securities.
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2.01
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Upon the terms and subject to the conditions herein contained (including the satisfaction or waiver of the closing conditions
set forth in Section 6), the Company agrees to sell and issue to each Purchaser, and each Purchaser agrees, severally and not jointly, to purchase from the Company, at a closing to take place remotely via exchange of executed
documents (the “Closing” and the date of the Closing, the “Closing Date”) to occur immediately prior to the Initial
Effective Time (as such term is defined in the Merger Agreement), (i) that number of Shares set forth under the heading “Shares” opposite such Purchaser’s name on the Schedule of Purchasers (which represents the portion of the Purchaser’s
Subscription Amount set forth on the Schedule of Purchasers (the “Subscription Amount”) divided by the Purchase Price (as may be adjusted pursuant to Section 2.04 hereof)
(rounded down to the nearest whole share)), and (ii) that number of
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