June 12, 2025 Robert Carter Chief Financial Officer Oncology Institute, Inc. 18000 Studebaker Rd Suite 800 Cerritos, CA 90703 Re: Oncology Institute, Inc. Registration Statement on Form S-3 Filed June 6, 2025 File No. 333-287848 Dear Robert Carter: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Robert Augustin at 202-551-8483 with any questions. Sincerely, Division of Corporation Finance Office of Industrial Applications and Services cc: Steven B. Stokdyk