United States securities and exchange commission logo June 8, 2022 Ajay Patel Chief Accounting Officer Assertio Holdings, Inc. 100 South Saunders Road, Suite 300 Lake Forest, IL 60045 Re: Assertio Holdings, Inc. Form 10-K filed March 10, 2022 File No. 001-39294 Dear Mr. Patel: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Life Sciences