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Exhibit 107

CALCULATION OF FILING FEE TABLES

Form S-3

(Form Type)

Nautilus Biotechnology, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered Securities

			Security Type			Security Class Title			Fee Calculation Rule			Amount Registered			Proposed Maximum Offering Price Per Unit			Maximum Aggregate Offering Price			Fee Rate			Amount of Registration Fee
Newly Registered Securities
Fees to Be Paid			Equity			Common Stock, par value $0.0001 per share			Rule 457(o)			(1)			(1)			(1) (2)			—			—
Fees to Be Paid			Equity			Preferred Stock, par value $0.0001 per share			Rule 457(o)			(1)			(1)			(1) (2)			—			—
Fees to Be Paid			Debt			Debt Securities			Rule 457(o)			(1)			(1)			(1) (2)			—			—
Fees to Be Paid			Equity			Depositary Shares			Rule 457(o)			(1)			(1)			(1) (2)			—			—
Fees to Be Paid			Equity			Warrants			Rule 457(o)			(1)			(1)			(1) (2)			—			—
Fees to Be Paid			Other			Subscription Rights			Rule 457(o)			(1)			(1)			(1) (2)			—			—
Fees to Be Paid			Other			Purchase Contracts			Rule 457(o)			(1)			(1)			(1) (2)			—			—
Fees to Be Paid			Other			Units			Rule 457(o)			(1)			(1)			(1) (2)			—			—
Fees to Be Paid			Unallocated (Universal) Shelf			Unallocated (Universal) Shelf			Rule 457(o)			(1)			(1)			$300,000,000			$0.00014760			$44,280
			Total Offering Amounts															$300,000,000						$44,280
			Total Fees Previously Paid																					—
			Total Fee Offsets																					—
			Net Fee Due																					$44,280

(1)An indeterminate aggregate initial offering price and number of securities of each identified class is being registered as may from time to time be offered, issued or sold at indeterminate prices. In addition, an indeterminate number of securities that may be issued upon exercise, settlement, conversion or exchange of any offered securities, or pursuant to anti-dilution adjustments, is being registered. Separate consideration may or may not be received for securities that are issuable on exercise, conversion or exchange of other securities.

(2)The proposed maximum offering price per security and proposed maximum aggregate offering price per class of security will be determined from time to time by the registrant in connection with the issuance by the registrant of the securities registered hereunder and is not specified as to each class of security pursuant to General Instruction II.D. of Form S-3 under the Securities Act. Separate consideration may or may not be received for securities that are issuable on exercise, conversion or exchange of other securities, or that are issued in units.