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Exhibit 8.1

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List of Subsidiaries

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Subsidiaries

 

Place of Incorporation

 

 

 

Adagene (Hong Kong) Limited

 

Hong Kong

 

 

 

Adagene (Suzhou) Limited

 

PRC

 

 

 

Adagene Incorporated

 

Delaware, United States

 

 

 

ADAGENE PTE. LTD.

 

Singapore

 

 

 

ADAGENE AUSTRALIA PTY LTD

 

Australia

 

 

 

ADAGENE AG

 

Switzerland

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Adagene Project C1 Pte. Ltd.

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Singapore

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Adagene (Suzhou) Limited Beijing Branch

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PRC

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