December 20, 2024 William F. Feehery Chief Executive Officer Certara, Inc. 4 Radnor Corporate Center, Suite 350 Radnor, PA 19087 Re: Certara, Inc. Form 10-K for Fiscal Year Ended December 31, 2023 Dear William F. Feehery: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Technology cc: Daniel D. Corcoran