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Exhibit 8.1
Subsidiaries of Pharming Group B.V.

Name of SubsidiaryState or Other Jurisdiction of Incorporation
Pharming Americas B.V.The Netherlands
Pharming Intellectual Property B.V.The Netherlands
Pharming Technologies B.V.The Netherlands
Pharming Research & Development B.V.
The Netherlands
Pharming Australia Pty Ltd
Australia
Pharming UK Ltd
The United Kingdom
Broekman Instituut B.V.The Netherlands
Pharming Healthcare, Inc.Delaware
ProBio, Inc.Delaware