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Exhibit 15.1

Consent of Independent Registered Public Accounting Firm

We consent to the incorporation by reference in the Registration Statements (Form S-8 Nos. 333-256403 and 333-264156) pertaining to Global-E Online Ltd. 2013 Share Option Plan and Global-E Online Ltd. 2021 Share Incentive Plan of Global-E Online Ltd. of our reports dated March 26, 2026, with respect to the consolidated financial statements of Global-E Online Ltd., and the effectiveness of internal control over financial reporting of Global-E Online Ltd., included in this Annual Report (Form 20-F) for the year ended December 31, 2025.

/S/ Kost Forer Gabbay & Kasierer
A Member of EY Global
  
Tel-Aviv, Israel
March 26, 2026