<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/schedule13g" xmlns:com="http://www.sec.gov/edgar/common">
  <headerData>
    <submissionType>SCHEDULE 13G</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0001851416</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <securitiesClassTitle>Common Stock, $0.0001 par value</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>09/26/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001840563</issuerCik>
        <issuerName>PMGC Holdings Inc.</issuerName>
        <issuerCusip>73017P300</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>120 NEWPORT CENTER DRIVE</com:street1>
          <com:street2>STE 250</com:street2>
          <com:city>NEWPORT BEACH</com:city>
          <com:stateOrCountry>CA</com:stateOrCountry>
          <com:zipCode>92660</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Streeterville Capital LLC</reportingPersonName>
      <citizenshipOrOrganization>UT</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>90452.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>90452.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>90452.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>9.9</classPercent>
      <typeOfReportingPerson>OO</typeOfReportingPerson>
      <comments>Reporting person Streeterville Capital, LLC ("Streeterville") has rights, under a Secured Pre-Paid Purchase #1, to own an aggregate number of shares of the Issuer's common stock which, except for a contractual cap on the amount of outstanding shares that Streeterville may own, would exceed such a cap. Streeterville's current ownership cap is 9.9%. Thus, the number of shares of the Issuer's common stock beneficially owned by Streeterville as of the date of this filing was 90,452 shares, which is 9.9% of the 913,664 shares outstanding on September 19, 2025 (as reported in the Issuer's S-1 filed on that date).</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Streeterville Management, LLC</reportingPersonName>
      <citizenshipOrOrganization>UT</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>90452.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>90452.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>90452.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>9.9</classPercent>
      <typeOfReportingPerson>OO</typeOfReportingPerson>
      <comments>Reporting person Streeterville Management, LLC is the Manager of Streeterville. Streeterville has rights, under a Secured Pre-Paid Purchase #1, to own an aggregate number of shares of the Issuer's common stock which, except for a contractual cap on the amount of outstanding shares that Streeterville may own, would exceed such a cap. Streeterville's current ownership cap is 9.9%. Thus, the number of shares of the Issuer's common stock beneficially owned by Streeterville as of the date of this filing was 90,452 shares, which is 9.9% of the 913,664 shares outstanding on September 19, 2025 (as reported in the Issuer's S-1 filed on that date).</comments>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>John M. Fife</reportingPersonName>
      <citizenshipOrOrganization>X1</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>90452.00</soleVotingPower>
        <sharedVotingPower>0.00</sharedVotingPower>
        <soleDispositivePower>90452.00</soleDispositivePower>
        <sharedDispositivePower>0.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>90452.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>9.9</classPercent>
      <typeOfReportingPerson>IN</typeOfReportingPerson>
      <comments>Reporting person John M Fife is the sole member of Streeterville Management, LLC, which is the Manager of Streeterville. Streeterville has rights, under a Secured Pre-Paid Purchase #1, to own an aggregate number of shares of the Issuer's common stock which, except for a contractual cap on the amount of outstanding shares that Streeterville may own, would exceed such a cap. Streeterville's current ownership cap is 9.9%. Thus, the number of shares of the Issuer's common stock beneficially owned by Streeterville as of the date of this filing was 90,452 shares, which is 9.9% of the 913,664 shares outstanding on September 19, 2025 (as reported in the Issuer's S-1 filed on that date).</comments>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>PMGC Holdings Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>120 NEWPORT CENTER DRIVE, STE 250, NEWPORT BEACH, CALIFORNIA, 92660</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>This report is filed by Streeterville Capital LLC, Streeterville Management LLC, and John M. Fife with respect to the shares of Common Stock, $0.0001 par value per share, of the Issuer that are directly beneficially owned by Streeterville Capital LLC and indirectly beneficially owned by the other reporting and filing persons.</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>300 East Randolph Street, Suite 40.150
Chicago, IL 60601</principalBusinessOfficeOrResidenceAddress>
        <citizenship>Streeterville Capital LLC is a Utah limited liability company.
Streeterville Management LLC is a Utah limited liability company.
John M. Fife is a United States citizen.</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>90,452</amountBeneficiallyOwned>
        <classPercent>9.9%</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>90,452</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>0</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>90,452</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>0</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
        <classOwnership5PercentOrLess>N</classOwnership5PercentOrLess>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>Y</notApplicableFlag>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under &amp;#167; 240.14a-11.

</certifications>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>Streeterville Capital LLC</reportingPersonName>
      <signatureDetails>
        <signature>John Fife</signature>
        <title>President</title>
        <date>09/29/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Streeterville Management, LLC</reportingPersonName>
      <signatureDetails>
        <signature>John Fife</signature>
        <title>President</title>
        <date>09/29/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>John M. Fife</reportingPersonName>
      <signatureDetails>
        <signature>John Fife</signature>
        <title>John Fife</title>
        <date>09/29/2025</date>
      </signatureDetails>
    </signatureInformation>
  </formData>
</edgarSubmission>