Exhibit 23.1

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CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

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We hereby consent to the incorporation by reference in the Registration Statement on Form S-8 (No. 333-256655) of LAVA Therapeutics N.V. of our report dated March 28, 2025 relating to the financial statements, which appears in this Form 10-K.

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/s/ PricewaterhouseCoopers Accountants N.V.

Eindhoven, The Netherlands

March 28, 2025