February 10, 2025 Rajiv Shukla Chief Executive Officer Carmell Corp 2403 Sidney Street, Suite 300 Pittsburgh, PA 15203 Re: Carmell Corp Registration Statement on Form S-3 Filed February 3, 2025 File No. 333-284670 Dear Rajiv Shukla: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Margaret Sawicki at 202-551-7153 with any questions. Sincerely, Division of Corporation Finance Office of Industrial Applications and Services cc: Michael Hedge, Esq.