Exhibit 107

Calculation of Filing Fee Table

Form S-4

(Form Type)

Alumis Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered Securities

Security Type

Security Class Title

Fee Calculation
Rule

Amount
Registered

Proposed Maximum
Offering Price Per
Unit

Maximum
Aggregate
Offering Price

Fee Rate

Amount of
Registration Fee

Fees to be Paid⁽¹⁾

Equity

Common Stock

457(f)

6,434,950

$5.07⁽²⁾

$32,625,196.50

0.00015310

$4,994.92

Total Offering Amounts

$32,625,196.50

$4,994.92

Total Fee Previously Paid

—

Total Fee Offsets

—

Net Fee Due

$4,994.92

(1)

Relates to 5,528,395 shares of voting common stock, $0.0001 par value per share (the “Common Stock”), of Alumis Inc. (“Alumis”), issuable to stockholders of ACELYRIN, Inc. (“ACELYRIN”) at the effective time of the proposed merger (the “Merger”) of Arrow Merger Sub, Inc., a wholly owned subsidiary of Alumis (“Merger Sub”), with and into ACELYRIN, with ACELYRIN surviving as a wholly owned subsidiary of Alumis, pursuant to the Agreement and Plan of Merger, dated as of February 6, 2025, as amended by that certain Amendment to Agreement and Plan of Merger, dated as of April 20, 2025, by and among Alumis, Merger Sub and ACELYRIN (the “Merger Agreement”), as well as shares of Common Stock underlying certain outstanding options, restricted stock unit awards and performance restricted stock unit awards of ACELYRIN to be converted into options and restricted stock unit awards of Alumis pursuant to the Merger Agreement, which conversion is to be covered by this registration statement (the “Registration Statement”). The shares underlying outstanding equity awards of Alumis include (i) up to 702,238 shares of Common Stock underlying stock options to be assumed by Alumis at the effective time of the Merger, (ii) up to 169,716 shares of Common Stock underlying restricted stock unit awards to be assumed by Alumis at the effective time of the Merger; (iii) up to 34,601 shares of Common Stock underlying performance restricted stock unit awards to be assumed by Alumis at the effective time of the Merger.

(2)

Estimated solely for the purpose of calculating the amount of the registration fee pursuant to Rules 457(f) and 457(c) under the Securities Act, based on the average of the high and low prices of the Common Stock as quoted on the Nasdaq Global Select Market on April 16, 2025, of $5.07 per share, which such date is within five business days of the filing of the Registration Statement.

Table 3: Combined Prospectuses


Security Type	Security Class Title	Amount of Securities Previously Registered	Maximum Aggregate Offering Price of Securities Previously Registered	Form Type	File Number	Initial Effective Date
Equity	Common Stock	50,931,434⁽¹⁾	$185,899,734.10	S-4	333-286178	April 4, 2025

(1)

Represents the issuance of up to 50,931,434 shares of Common Stock in connection with the Merger that will be included in a combined prospectus in connection with this Registration Statement and the registration statement on Form S-4 (File No. 333-286178), which was originally filed on March 27, 2025 and declared effective on April 4, 2025 (the “Prior Registration Statement”), pursuant to Rule 429 under the Securities Act. No registration fee is payable in connection with such securities, which were previously registered on the Prior Registration Statement. See “Explanatory Note and Statement Pursuant to Rule 429” in this Registration Statement.