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Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Checkbox not checked   Rule 13d-1(b)
Checkbox checked   Rule 13d-1(c)
Checkbox not checked   Rule 13d-1(d)






SCHEDULE 13G




Comment for Type of Reporting Person:   These securities are held of record by TCG Crossover II (as defined in Item 2(a) below). TCG Crossover GP II (as defined in Item 2(a) below) is the general partner of TCG Crossover II and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP II and may be deemed to share voting, investment and dispositive power with respect to these securities. This total excludes (i) 8,514,089 shares of Common Stock subject to Pre-Funded Warrants and (ii) 8,695,652 shares of Common Stock subject to Common Stock Warrants (together with the Pre-Funded Warrants, the Warrants) which are not exercisable within 60 days of this Statement because the Warrants may not be exercised to the extent that doing so would result in the holder of the Warrants and (together with the holder's affiliates and any other persons acting as a group together with the holder or any of the holder's affiliates) beneficially owning more than 9.99 percent of the shares of Common Stock then outstanding immediately after giving effect to such exercise (the Beneficial Ownership Limitation). Based on 179,337,686 shares of Common Stock outstanding as of January 9, 2026, as provided to the Reporting Persons by the Issuer (as defined in Item 1(a) below).


SCHEDULE 13G




Comment for Type of Reporting Person:   These securities are held of record by TCG Crossover II. TCG Crossover GP II is the general partner of TCG Crossover II and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP II and may be deemed to share voting, investment and dispositive power with respect to these securities. This total excludes (i) 8,514,089 shares of Common Stock subject to Pre-Funded Warrants and (ii) 8,695,652 shares of Common Stock subject to Common Stock Warrants held by TCG Crossover II which are not exercisable within 60 days of this Statement due to the Beneficial Ownership Limitation. Based on 179,337,686 shares of Common Stock outstanding as of January 9, 2026, as provided to the Reporting Persons by the Issuer.


SCHEDULE 13G




Comment for Type of Reporting Person:   These securities are held of record by TCG Crossover III (as defined in Item 2(a) below). TCG Crossover GP III (as defined in Item 2(a) below) is the general partner of TCG Crossover III and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP III and may be deemed to share voting, investment and dispositive power with respect to these securities. This total excludes (i) 8,514,089 shares of Common Stock subject to Pre-Funded Warrants and (ii) 8,695,652 shares of Common Stock subject to Common Stock Warrants held by TCG Crossover III which are not exercisable within 60 days of this Statement due to the Beneficial Ownership Limitation. Based on 179,337,686 shares of Common Stock outstanding as of January 9, 2026, as provided to the Reporting Persons by the Issuer.


SCHEDULE 13G




Comment for Type of Reporting Person:   These securities are held of record by TCG Crossover III. TCG Crossover GP III is the general partner of TCG Crossover III and may be deemed to have voting, investment, and dispositive power with respect to these securities. Chen Yu is the sole managing member of TCG Crossover GP III and may be deemed to share voting, investment and dispositive power with respect to these securities. This total excludes (i) 8,514,089 shares of Common Stock subject to Pre-Funded Warrants and (ii) 8,695,652 shares of Common Stock subject to Common Stock Warrants held by TCG Crossover III which are not exercisable within 60 days of this Statement due to the Beneficial Ownership Limitation. Based on 179,337,686 shares of Common Stock outstanding as of January 9, 2026, as provided to the Reporting Persons by the Issuer.


SCHEDULE 13G




Comment for Type of Reporting Person:   Consists of (i) 8,877,215 shares of Common Stock held of record by TCG Crossover II and (ii) 8,877,215 shares of Common Stock held of record by TCG Crossover III. TCG Crossover GP II is the general partner of TCG Crossover II and may be deemed to have voting, investment, and dispositive power with respect to the securities held of record by TCG Crossover II. TCG Crossover GP III is the general partner of TCG Crossover III and may be deemed to have voting, investment, and dispositive power with respect to the securities held of record by TCG Crossover III. Chen Yu is the sole managing member of each of TCG Crossover GP II and TCG Crossover GP III and may be deemed to share voting, investment and dispositive power with respect to the securities held of record by TCG Crossover II and TCG Crossover III. This total excludes (i) 8,514,089 shares of Common Stock subject to Pre-Funded Warrants held by TCG Crossover II, (ii) 8,695,652 shares of Common Stock subject to Common Stock Warrants held by TCG Crossover II, (iii) 8,514,089 shares of Common Stock subject to Pre-Funded Warrants held by TCG Crossover III and (iv) 8,695,652 shares of Common Stock subject to Common Stock Warrants held by TCG Crossover III which are not exercisable within 60 days of this Statement due to the Beneficial Ownership Limitation. Based on 179,337,686 shares of Common Stock outstanding as of January 9, 2026, as provided to the Reporting Persons by the Issuer.


SCHEDULE 13G



 
TCG Crossover GP II, LLC
 
Signature:/s/ Craig Skaling
Name/Title:Craig Skaling, Authorized Signatory
Date:01/15/2026
 
TCG Crossover Fund II, L.P.
 
Signature:/s/ Craig Skaling
Name/Title:Craig Skaling, Authorized Signatory
Date:01/15/2026
 
TCG Crossover GP III, LLC
 
Signature:/s/ Craig Skaling
Name/Title:Craig Skaling, Authorized Signatory
Date:01/15/2026
 
TCG Crossover Fund III, L.P.
 
Signature:/s/ Craig Skaling
Name/Title:Craig Skaling, Authorized Signatory
Date:01/15/2026
 
Chen Yu
 
Signature:/s/ Craig Skaling
Name/Title:Craig Skaling, as Attorney-in-Fact for Chen Yu
Date:01/15/2026