Exhibit 23.1
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| KPMG LLP Two Financial Center 60 South Street Boston, MA 02111 |
Consent of Independent Registered Public Accounting Firm
We consent to the use of our report dated February 26, 2026, with respect to the consolidated financial statements of Nuvalent, Inc., and the effectiveness of internal control over financial reporting, incorporated herein by reference.
| /s/ KPMG LLP |
Boston, Massachusetts
February 26, 2026
| KPMG LLP, a Delaware limited liability partnership, and its subsidiaries are part of the KPMG global organization of independent member firms affiliated with KPMG International Limited, a private English company limited by guarantee. |