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S-3 S-3 EX-FILING FEES 0001875558 Nuvectis Pharma, Inc. N/A 0.0001381 0.0001381 0.0001381 0.0001381 0.0001381 0.0001381 Y N 0001875558 2026-02-12 2026-02-12 0001875558 1 2026-02-12 2026-02-12 0001875558 2 2026-02-12 2026-02-12 0001875558 3 2026-02-12 2026-02-12 0001875558 4 2026-02-12 2026-02-12 0001875558 5 2026-02-12 2026-02-12 0001875558 6 2026-02-12 2026-02-12 0001875558 7 2026-02-12 2026-02-12 0001875558 1 2026-02-12 2026-02-12 0001875558 2 2026-02-12 2026-02-12 iso4217:USD xbrli:pure xbrli:shares

Calculation of Filing Fee Tables

S-3

Nuvectis Pharma, Inc.

Table 1: Newly Registered and Carry Forward Securities ☐Not Applicable

Security Type

Security Class Title

Fee Calculation or Carry Forward Rule

Amount Registered

Proposed Maximum Offering Price Per Unit

Maximum Aggregate Offering Price

Fee Rate

Amount of Registration Fee

Carry Forward Form Type

Carry Forward File Number

Carry Forward Initial Effective Date

Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward

Newly Registered Securities
Equity Common Stock, $0.00001 par value per share 457(o)
Equity Preferred Stock, $0.00001 par value per share 457(o)
Debt Debt Securities 457(o)
Other Warrants 457(o)
Other Units 457(o)
Other Subscription Rights 457(o)
Fees to be Paid 1 Unallocated (Universal) Shelf 457(o) $ 150,000,000.00 0.0001381 $ 20,715.00
Fees Previously Paid
Carry Forward Securities
Carry Forward Securities

Total Offering Amounts:

$ 150,000,000.00

$ 20,715.00

Total Fees Previously Paid:

$ 0.00

Total Fee Offsets:

$ 11,403.86

Net Fee Due:

$ 9,311.14

Offering Note

1

a) Represents securities that may be offered and sold from time to time in one or more offerings by Nuvectis Pharma, Inc. (the "Registrant"). b) There are being registered hereunder an indeterminate number of shares of common stock and preferred stock, an indeterminate principal amount of debt securities, an indeterminate number of warrants to purchase common stock, preferred stock or debt securities, an indeterminate number of units, and an indeterminate number of subscription rights to purchase an indeterminate number of common stock or preferred stock, from time to time, which together shall have an aggregate initial offering price not to exceed $150,000,000. If any debt securities are issued at an original issue discount, then the offering price of such debt securities shall be in such greater principal as shall result in an aggregate offering price not to exceed $150,000,000 less the aggregate dollar amount of all securities previously issued hereunder. Any securities registered hereunder may be sold separately or as units with other securities registered hereunder. The proposed maximum offering price of the securities will be determined, from time to time, by the Registrant in connection with the issuance by the Registrant of the securities registered hereunder. The securities registered hereunder also include an indeterminate number of shares of common stock and preferred stock and amount of debt securities as may be issued upon conversion of or exchange for preferred stock or debt securities that provide for conversion or exchange, upon exercise of warrants or subscription rights or pursuant to the anti-dilution provisions of any the securities registered hereunder. In addition, pursuant to Rule 416 under the Securities Act of 1933, as amended (the "Securities Act"), the shares being registered hereunder include an indeterminate number of shares of common stock and preferred stock as may be issuable with respect to the shares being registered hereunder as a result of stock splits, stock dividends or similar transactions. c) The proposed maximum aggregate offering price reflected in the table has been estimated solely for purposes of calculating the registration fee pursuant to Rule 457(o) under the Securities Act.

Table 2: Fee Offset Claims and Sources ☐Not Applicable
Registrant or Filer Name Form or Filing Type File Number Initial Filing Date Filing Date Fee Offset Claimed Security Type Associated with Fee Offset Claimed Security Title Associated with Fee Offset Claimed Unsold Securities Associated with Fee Offset Claimed Unsold Aggregate Offering Amount Associated with Fee Offset Claimed Fee Paid with Fee Offset Source
Rules 457(b) and 0-11(a)(2)
Fee Offset Claims
Fee Offset Sources
Rule 457(p)
Fee Offset Claims 1 Nuvectis Pharma, Inc. S-3 333-270657 03/17/2023 $ 11,403.86 Unallocated (Universal) Shelf Unallocated (Universal) Shelf $ 103,483,282.81
Fee Offset Sources Nuvectis Pharma, Inc. S-3 333-270657 03/17/2023 $ 11,403.86

Rule 457(p) Statement of Withdrawal, Termination, or Completion:

1

Pursuant to Rule 415(a)(6) under the Securities Act, the securities registered pursuant to this registration statement include $103,483,281.81 of unsold securities (the "Unsold Securities") previously registered on the registrant's registration statement on Form S-3 (File No. 333-270657), which was initially filed with the Securities and Exchange Commission on March 17, 2023 (the "Prior Registration Statement") and had a proposed maximum aggregate offering price of $150,000,000. The registrant sold an aggregate of $46,516,718.19 of such securities under the Prior Registration Statement, leaving the balance of $103,483,281.81 of Unsold Securities, in respect of which the registrant paid an aggregate registration fee of $11,403.86 (calculated at the filing fee rate which was in effect at the time of the filing of the Prior Registration Statement) relating to the Unsold Securities under the Prior Registration Statement. No additional filing fee is due with respect to the Unsold Securities in connection with the filing of this registration statement. A filing fee of $9,311.14 is paid herewith in connection with the $46,516,718.19 of additional securities registered hereunder. Pursuant to Rule 415(a)(6) under the Securities Act, the offering of Unsold Securities under the Prior Registration Statement will be deemed terminated as of the date of effectiveness of this registration statement.

Table 3: Combined Prospectuses ☑Not Applicable

Security Type

Security Class Title

Amount of Securities Previously Registered

Maximum Aggregate Offering Price of Securities Previously Registered

Form Type

File Number

Initial Effective Date

N/A N/A N/A N/A N/A N/A N/A N/A