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Exhibit 107

Calculation of Filing Fee Tables

Form S-3

(Form Type)

Prime Medicine, Inc. 

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

			Security Type			Security Class Title			Fee Calculation or Carry Forward Rule			Amount Registered (1)(2)			Proposed Maximum Offering Price Per Unit (3)			Maximum Aggregate Offering Price (3)			Fee Rate			Amount of Registration Fee			Carry Forward Form Type			Carry Forward File Number			Carry Forward Initial Effective Date			Filing Fee Previously Paid In Connection with Unsold Securities to be Carried Forward
Newly Registered Securities
Fees to Be Paid			Equity			Common Stock, $0.00001 par value per share			457(c)			11,006,163			$3.34			$36,760,584.42			0.00015310			$5,628.05			-			-			-			-
Carry Forward Securities
Carry Forward Securities			-			-			-			-			-			-			-			-			-			-			-			-
			Total Offering Amounts															$36,760,584.42						$5,628.05
			Total Fees Previously Paid																					-
			Total Fee Offsets																					-
			Net Fee Due																					$5,628.05

(1) The registrant is hereby registering for resale or other disposition, from time to time, by the selling stockholder (the “selling stockholder”) named in the prospectus that forms a part of this registration statement (this “registration statement”) an aggregate of up to 11,006,163 shares of the registrant’s common stock, par value $0.00001 per share (the “common stock”). Pursuant to Rule 416 under the Securities Act of 1933, as amended (the “Securities Act”), this registration statement also covers any additional number of shares of common stock issuable upon stock splits, stock dividends, or other distribution, recapitalization or similar events with respect to the shares of common stock being registered pursuant to this registration statement.

(2) Represents the maximum number of shares of the common stock that may be offered and sold, from time to time, by the selling stockholder, which shares were issued to the selling stockholder in a private placement.

(3) Estimated solely for the purpose of calculating the registration fee in accordance with Rule 457(c) under the Securities Act. The price per share and aggregate offering price are based on the average of the high and low prices of the registrant’s common stock on December 9, 2024, as reported on The Nasdaq Global Market.