| Name of Subsidiary | State or Jurisdiction of Incorporation or Organization | |||||||
Zymeworks CallCo ULC | Province of British Columbia | |||||||
Zymeworks ExchangeCo Ltd. | Province of British Columbia | |||||||
Zymeworks BC Inc. | Province of British Columbia | |||||||
Zymeworks Management Inc. | Province of British Columbia | |||||||
| Zymeworks Management Inc. (UK Establishment) | United Kingdom | |||||||
Zymeworks Biopharmaceuticals Inc. | Washington | |||||||
Zymeworks Pharmaceuticals Limited | Ireland | |||||||
Zymeworks Lifesciences Pte. Ltd. | Singapore | |||||||
* | Inclusion on the list above is not an admission that any of the above entities, individually or in the aggregate, constitutes a significant subsidiary within the meaning of Rule 1-02(w) of Regulation S-X and Item 601(b)(21)(ii) of Regulation S-K. | ||||