| Name of Subsidiary | State or Jurisdiction of Incorporation or Organization | |||||||||||||||||||||||||
Zymeworks CallCo ULC | Province of British Columbia | |||||||||||||||||||||||||
Zymeworks ExchangeCo Ltd. | Province of British Columbia | |||||||||||||||||||||||||
Zymeworks BC Inc. | Province of British Columbia | |||||||||||||||||||||||||
Zymeworks Management Inc. | Province of British Columbia | |||||||||||||||||||||||||
Zymeworks Royalty Partnership Limited | Province of British Columbia | |||||||||||||||||||||||||
Zymeworks General Partner ULC | Province of British Columbia | |||||||||||||||||||||||||
| Zymeworks Management Inc. (UK Establishment) | United Kingdom | |||||||||||||||||||||||||
Zymeworks Biopharmaceuticals Inc. | Washington | |||||||||||||||||||||||||
Zymeworks Pharmaceuticals Limited | Ireland | |||||||||||||||||||||||||
Zymeworks Lifesciences Pte. Ltd. | Singapore | |||||||||||||||||||||||||
* | Inclusion on the list above is not an admission that any of the above entities, individually or in the aggregate, constitutes a significant subsidiary within the meaning of Rule 1-02(w) of Regulation S-X and Item 601(b)(21)(ii) of Regulation S-K. | ||||||||||||||||