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Exhibit 8.1

LIST OF PRINCIPAL SUBSIDIARIES OF THE REGISTRANT

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Name

    

Place of Incorporation

Alpine Bioscience Ltd

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British Virgin Islands

Adlai Nortye Pte. Ltd.

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Singapore

Adlai Nortye (HK) Limited

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Hong Kong

Adlai Nortye (Switzerland) AG

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Switzerland

Adlai Nortye Biopharma Co., Ltd.

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PRC

Adlai Nortye USA INC

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United States

Shanghai Adlai Nortye Biopharma Co., Ltd.

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PRC

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