Exhibit 8.1
LIST OF PRINCIPAL SUBSIDIARIES OF THE REGISTRANT
| Name | Place of Incorporation | |
| Alpine Bioscience Ltd | British Virgin Islands | |
| Adlai Nortye Pte. Ltd. | Singapore | |
| Adlai Nortye (HK) Limited | Hong Kong | |
| Adlai Nortye (Switzerland) AG | Switzerland | |
| Adlai Nortye Biopharma Co., Ltd. | PRC | |
| Adlai Nortye USA INC | United States | |
| Shanghai Adlai Nortye Biopharma Co., Ltd. | PRC |